Metal Gear Solid: Portable Ops redefines the stealth action genre for handheld gaming systems with an original storyline that follows from the events of Metal Gear Solid 3: Snake Eater and boasts ground-breaking online play that lets gamers recruit comrades to form a unique fighting force.

The single-player campaign of Metal Gear Solid: Portable Ops follows the events of Metal Gear Solid 3: Snake Eater, as Big Boss establishes FOXHOUND in an attempt to hunt down the treacherous FOX unit, which has started a bloody revolt in South America. Set in 1970, the game will be the missing link in the ongoing Metal Gear saga, as players will learn more about returning characters such as Para-Medic, Major Zero and Sigint and also witness Big Boss's greatest tragedy - a loss that sets into motion the events of later games in the Metal Gear Solid timeline.