Many years have passed since the darkness of Damian's armies was repelled and Damian was banished into another realm by man's Demigod hero, the Divine. While men enjoy their first years of real peace, Damian breaks free from his bonds and returns to the world of Rivellon to take vengeance on he who imprisoned him. To do so, Damian takes control of the minds of the world's rarest and most powerful beings: the Dragon Knights, whom he unleashes on to the world. It is one of them who kills the Divine. With the dragons now on the side of evil, many young men and women of Rivellon have taken up the role of ridding the world of these dragons - they are known as Dragon Slayers.

In Divinity II: Ego Draconis, players find themselves once again in Rivellon, a timeless world full of awe and magic, shattered and frightened by the apocalyptic wars of the past.

Players begin as a Dragon Slayer, hunters whom travel the countryside determined to rid their lands of Dragons. As the story of Divinity II: Ego Draconis unfolds, the player will discover new abilities and possibilities as they evolve into a legendary Dragon Lord. In addition, the player character's abilities can be steadily improved over the course of the game and specialised in specific areas. The world of Divinity II: Ego Draconis is filled with humans and fantasy creatures, each having special combat abilities. Players will need to use every skill, potion and hidden trick to their strategic advantage to reclaim the lands of Rivellon.